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Priming by Chemokines Restricts Lateral Mobility of the Adhesion Receptor LFA-1 and Restores Adhesion to ICAM-1 Nano-Aggregates on Human Mature Dendritic Cells
LFA-1 is a leukocyte specific β(2) integrin that plays a major role in regulating adhesion and migration of different immune cells. Recent data suggest that LFA-1 on mature dendritic cells (mDCs) may function as a chemokine-inducible anchor during homing of DCs through the afferent lymphatics into t...
Autores principales: | Borgman, Kyra J. E., van Zanten, Thomas S., Manzo, Carlo, Cabezón, Raquel, Cambi, Alessandra, Benítez-Ribas, Daniel, Garcia-Parajo, Maria F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063950/ https://www.ncbi.nlm.nih.gov/pubmed/24945611 http://dx.doi.org/10.1371/journal.pone.0099589 |
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