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The Calcium-Dependent Protein Kinase 3 of Toxoplasma Influences Basal Calcium Levels and Functions beyond Egress as Revealed by Quantitative Phosphoproteome Analysis

Calcium-dependent protein kinases (CDPKs) are conserved in plants and apicomplexan parasites. In Toxoplasma gondii, TgCDPK3 regulates parasite egress from the host cell in the presence of a calcium-ionophore. The targets and the pathways that the kinase controls, however, are not known. To identify...

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Detalles Bibliográficos
Autores principales: Treeck, Moritz, Sanders, John L., Gaji, Rajshekhar Y., LaFavers, Kacie A., Child, Matthew A., Arrizabalaga, Gustavo, Elias, Joshua E., Boothroyd, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063958/
https://www.ncbi.nlm.nih.gov/pubmed/24945436
http://dx.doi.org/10.1371/journal.ppat.1004197