Enhanced Vaccine-Induced CD8(+) T Cell Responses to Malaria Antigen ME-TRAP by Fusion to MHC Class II Invariant Chain

The orthodox role of the invariant chain (CD74; Ii) is in antigen presentation to CD4(+) T cells, but enhanced CD8(+) T cells responses have been reported after vaccination with vectored viral vaccines encoding a fusion of Ii to the antigen of interest. In this study we assessed whether fusion of th...

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Detalles Bibliográficos
Autores principales: Spencer, Alexandra J., Cottingham, Matthew G., Jenks, Jennifer A., Longley, Rhea J., Capone, Stefania, Colloca, Stefano, Folgori, Antonella, Cortese, Riccardo, Nicosia, Alfredo, Bregu, Migena, Hill, Adrian V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063960/
https://www.ncbi.nlm.nih.gov/pubmed/24945248
http://dx.doi.org/10.1371/journal.pone.0100538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063960/
https://www.ncbi.nlm.nih.gov/pubmed/24945248
http://dx.doi.org/10.1371/journal.pone.0100538

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