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(64)Cu Labeled Sarcophagine Exendin-4 for MicroPET Imaging of Glucagon like Peptide-1 Receptor Expression

The Glucagon-like peptide 1 receptor (GLP-1R) has become an important target for imaging due to its elevated expression profile in pancreatic islets, insulinoma, and the cardiovascular system. Because native GLP-1 is degraded rapidly by dipeptidyl peptidase-IV (DPP-IV), several studies have conjugat...

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Detalles Bibliográficos
Autores principales: Wu, Zhanhong, Liu, Shuanglong, Nair, Indu, Omori, Keiko, Scott, Stephen, Todorov, Ivan, Shively, John E., Conti, Peter S., Li, Zibo, Kandeel, Fouad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063975/
https://www.ncbi.nlm.nih.gov/pubmed/24955138
http://dx.doi.org/10.7150/thno.7759