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(64)Cu Labeled Sarcophagine Exendin-4 for MicroPET Imaging of Glucagon like Peptide-1 Receptor Expression
The Glucagon-like peptide 1 receptor (GLP-1R) has become an important target for imaging due to its elevated expression profile in pancreatic islets, insulinoma, and the cardiovascular system. Because native GLP-1 is degraded rapidly by dipeptidyl peptidase-IV (DPP-IV), several studies have conjugat...
Autores principales: | Wu, Zhanhong, Liu, Shuanglong, Nair, Indu, Omori, Keiko, Scott, Stephen, Todorov, Ivan, Shively, John E., Conti, Peter S., Li, Zibo, Kandeel, Fouad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063975/ https://www.ncbi.nlm.nih.gov/pubmed/24955138 http://dx.doi.org/10.7150/thno.7759 |
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