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The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression

With aging, abnormal benign growth of the prostate results in benign prostate hyperplasia (BPH) with concomitant lower urinary tract symptoms (LUTS). Because the prostate is an androgen target tissue, and transforms testosterone into 5α-dihydrotestosterone (5α-DHT), a potent androgen, via 5α-reducta...

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Detalles Bibliográficos
Autores principales: Traish, Abdulmaged M., Mulgaonkar, Ashwini, Giordano, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Urological Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064044/
https://www.ncbi.nlm.nih.gov/pubmed/24955220
http://dx.doi.org/10.4111/kju.2014.55.6.367