Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor

BACKGROUND: The constitutive androstane receptor (CAR) plays a key role in the control of drug metabolism and transport by mediating the phenobarbital-type induction of many phase I and II drug metabolizing enzymes and drug transporters. RESULTS: We identified transcripts generated by four different...

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Detalles Bibliográficos
Autores principales: Arnold, Katja A, Eichelbaum, Michel, Burk, Oliver
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406421/
https://www.ncbi.nlm.nih.gov/pubmed/15043764
http://dx.doi.org/10.1186/1478-1336-2-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406421/
https://www.ncbi.nlm.nih.gov/pubmed/15043764
http://dx.doi.org/10.1186/1478-1336-2-1

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