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Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor
BACKGROUND: The constitutive androstane receptor (CAR) plays a key role in the control of drug metabolism and transport by mediating the phenobarbital-type induction of many phase I and II drug metabolizing enzymes and drug transporters. RESULTS: We identified transcripts generated by four different...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406421/ https://www.ncbi.nlm.nih.gov/pubmed/15043764 http://dx.doi.org/10.1186/1478-1336-2-1 |