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Modular and configurable optimal sequence alignment software: Cola
BACKGROUND: The fundamental challenge in optimally aligning homologous sequences is to define a scoring scheme that best reflects the underlying biological processes. Maximising the overall number of matches in the alignment does not always reflect the patterns by which nucleotides mutate. Efficient...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064277/ https://www.ncbi.nlm.nih.gov/pubmed/24976859 http://dx.doi.org/10.1186/1751-0473-9-12 |