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Modular and configurable optimal sequence alignment software: Cola
BACKGROUND: The fundamental challenge in optimally aligning homologous sequences is to define a scoring scheme that best reflects the underlying biological processes. Maximising the overall number of matches in the alignment does not always reflect the patterns by which nucleotides mutate. Efficient...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064277/ https://www.ncbi.nlm.nih.gov/pubmed/24976859 http://dx.doi.org/10.1186/1751-0473-9-12 |