Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment

BACKGROUND: Translational research typically aims to identify and functionally validate individual, disease-specific genes. However, reaching this aim is complicated by the involvement of thousands of genes in common diseases, and that many of those genes are pleiotropic, that is, shared by several...

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Detalles Bibliográficos
Autores principales: Gustafsson, Mika, Edström, Måns, Gawel, Danuta, Nestor, Colm E, Wang, Hui, Zhang, Huan, Barrenäs, Fredrik, Tojo, James, Kockum, Ingrid, Olsson, Tomas, Serra-Musach, Jordi, Bonifaci, Núria, Pujana, Miguel Angel, Ernerudh, Jan, Benson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064311/
https://www.ncbi.nlm.nih.gov/pubmed/24571673
http://dx.doi.org/10.1186/gm534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064311/
https://www.ncbi.nlm.nih.gov/pubmed/24571673
http://dx.doi.org/10.1186/gm534

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