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Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment
BACKGROUND: Translational research typically aims to identify and functionally validate individual, disease-specific genes. However, reaching this aim is complicated by the involvement of thousands of genes in common diseases, and that many of those genes are pleiotropic, that is, shared by several...
Autores principales: | Gustafsson, Mika, Edström, Måns, Gawel, Danuta, Nestor, Colm E, Wang, Hui, Zhang, Huan, Barrenäs, Fredrik, Tojo, James, Kockum, Ingrid, Olsson, Tomas, Serra-Musach, Jordi, Bonifaci, Núria, Pujana, Miguel Angel, Ernerudh, Jan, Benson, Mikael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064311/ https://www.ncbi.nlm.nih.gov/pubmed/24571673 http://dx.doi.org/10.1186/gm534 |
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