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A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. METHODS: In order to gain insights into the molecular pathways underlying prog...

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Detalles Bibliográficos
Autores principales: Campbell, Joshua D, McDonough, John E, Zeskind, Julie E, Hackett, Tillie L, Pechkovsky, Dmitri V, Brandsma, Corry-Anke, Suzuki, Masaru, Gosselink, John V, Liu, Gang, Alekseyev, Yuriy O, Xiao, Ji, Zhang, Xiaohui, Hayashi, Shizu, Cooper, Joel D, Timens, Wim, Postma, Dirkje S, Knight, Darryl A, Lenburg, Marc E, Hogg, James C, Spira, Avrum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064320/
https://www.ncbi.nlm.nih.gov/pubmed/22937864
http://dx.doi.org/10.1186/gm367