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Uridine prevents tamoxifen-induced liver lipid droplet accumulation

BACKGROUND: Tamoxifen, an agonist of estrogen receptor, is widely prescribed for the prevention and long-term treatment of breast cancer. A side effect of tamoxifen is fatty liver, which increases the risk for non-alcoholic fatty liver disease. Prevention of tamoxifen-induced fatty liver has the pot...

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Detalles Bibliográficos
Autores principales: Le, Thuc T, Urasaki, Yasuyo, Pizzorno, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064512/
https://www.ncbi.nlm.nih.gov/pubmed/24887406
http://dx.doi.org/10.1186/2050-6511-15-27