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Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury

Following brain injury, microglia assume a reactive-like state and secrete pro-inflammatory molecules that can potentiate damage. A therapeutic strategy that may limit microgliosis is of potential interest. In this context, selective estrogen receptor modulators, such as raloxifene and tamoxifen, ar...

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Detalles Bibliográficos
Autores principales: Barreto, George E., Santos-Galindo, Maria, Garcia-Segura, Luis Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064706/
https://www.ncbi.nlm.nih.gov/pubmed/24999330
http://dx.doi.org/10.3389/fnagi.2014.00132