Pathways for Small Molecule Delivery to the Central Nervous System Across the Blood-Brain Barrier

The treatment of central nervous system (CNS) disease has long been difficult due to the ineffectiveness of drug delivery across the blood-brain barrier (BBB). This review summarizes important concepts of the BBB in normal versus pathophysiology and how this physical, enzymatic, and efflux barrier p...

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Detalles Bibliográficos
Autores principales: Mikitsh, John L, Chacko, Ann-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064947/
https://www.ncbi.nlm.nih.gov/pubmed/24963272
http://dx.doi.org/10.4137/PMC.S13384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064947/
https://www.ncbi.nlm.nih.gov/pubmed/24963272
http://dx.doi.org/10.4137/PMC.S13384

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