mTORC2 Phosphorylation of Akt1: A Possible Mechanism for Hydrogen Sulfide-Induced Cardioprotection

Hydrogen sulfide (H(2)S) is known to have cardiac protective effects through Akt activation. Akt acts as a ‘central sensor’ for myocyte survival or death; its activity is regulated by multiple kinases including PI3K, mTORC2, PDK1 and phosphatases including PTEN, PP2A and PHLPPL. Based on the previou...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Wang, Daying, Gao, Xiufang, Lew, Karsheng, Richards, Arthur Mark, Wang, Peipei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064967/
https://www.ncbi.nlm.nih.gov/pubmed/24949720
http://dx.doi.org/10.1371/journal.pone.0099665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064967/
https://www.ncbi.nlm.nih.gov/pubmed/24949720
http://dx.doi.org/10.1371/journal.pone.0099665

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