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Celecoxib Sensitizes Staphylococcus aureus to Antibiotics in Macrophages by Modulating SIRT1

We have previously shown that celecoxib in combination with an antibiotic, increase the bacterial sensitivity to antibiotics. However, the underlying molecular mechanism remained elusive. Efficacy of the combinatorial treatment of celecoxib and ampicillin in vitro was evaluated on macrophage-phagocy...

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Detalles Bibliográficos
Autores principales: Annamanedi, Madhavi, Kalle, Arunasree M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064976/
https://www.ncbi.nlm.nih.gov/pubmed/24950067
http://dx.doi.org/10.1371/journal.pone.0099285