Translation of the radioresistance kinase TLK1B is induced by γ-irradiation through activation of mTOR and phosphorylation of 4E-BP1

BACKGROUND: The mammalian protein kinase TLK1 is a homologue of Tousled, a gene involved in flower development in Arabidopsis thaliana. The function of TLK1 is not well known, although knockout of the gene in Drosophila, or expression of a dominant negative mutant in mouse cells causes loss of nucle...

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Detalles Bibliográficos
Autores principales: Sunavala-Dossabhoy, Gulshan, Fowler, Marcie, De Benedetti, Arrigo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406498/
https://www.ncbi.nlm.nih.gov/pubmed/15070431
http://dx.doi.org/10.1186/1471-2199-5-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406498/
https://www.ncbi.nlm.nih.gov/pubmed/15070431
http://dx.doi.org/10.1186/1471-2199-5-1

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