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Translation of the radioresistance kinase TLK1B is induced by γ-irradiation through activation of mTOR and phosphorylation of 4E-BP1
BACKGROUND: The mammalian protein kinase TLK1 is a homologue of Tousled, a gene involved in flower development in Arabidopsis thaliana. The function of TLK1 is not well known, although knockout of the gene in Drosophila, or expression of a dominant negative mutant in mouse cells causes loss of nucle...
Autores principales: | Sunavala-Dossabhoy, Gulshan, Fowler, Marcie, De Benedetti, Arrigo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406498/ https://www.ncbi.nlm.nih.gov/pubmed/15070431 http://dx.doi.org/10.1186/1471-2199-5-1 |
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