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Morphine Enhances HIV-1(SF162)-Mediated Neuron Death and Delays Recovery of Injured Neurites

HIV-1 enters the CNS soon after initial systemic infection; within the CNS parenchyma infected and/or activated perivascular macrophages, microglia and astrocytes release viral and cellular toxins that drive secondary toxicity in neurons and other cell types. Our previous work has largely modeled HI...

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Detalles Bibliográficos
Autores principales: Masvekar, Ruturaj R., El-Hage, Nazira, Hauser, Kurt F., Knapp, Pamela E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064991/
https://www.ncbi.nlm.nih.gov/pubmed/24949623
http://dx.doi.org/10.1371/journal.pone.0100196