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BRCA1 Haploinsufficiency Leads to Altered Expression of Genes Involved in Cellular Proliferation and Development

The assessment of BRCA1 and BRCA2 coding sequences to identify pathogenic mutations associated with inherited breast/ovarian cancer syndrome has provided a method to identify high-risk individuals, allowing them to seek preventative treatments and strategies. However, the current test is expensive,...

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Detalles Bibliográficos
Autores principales: Feilotter, Harriet E., Michel, Claire, Uy, Paolo, Bathurst, Lauren, Davey, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064996/
https://www.ncbi.nlm.nih.gov/pubmed/24950059
http://dx.doi.org/10.1371/journal.pone.0100068