Ablation of Coactivator Med1 Switches the Cell Fate of Dental Epithelia to That Generating Hair

Cell fates are determined by specific transcriptional programs. Here we provide evidence that the transcriptional coactivator, Mediator 1 (Med1), is essential for the cell fate determination of ectodermal epithelia. Conditional deletion of Med1 in vivo converted dental epithelia into epidermal epith...

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Detalles Bibliográficos
Autores principales: Yoshizaki, Keigo, Hu, Lizhi, Nguyen, Thai, Sakai, Kiyoshi, He, Bing, Fong, Chak, Yamada, Yoshihiko, Bikle, Daniel D., Oda, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065011/
https://www.ncbi.nlm.nih.gov/pubmed/24949995
http://dx.doi.org/10.1371/journal.pone.0099991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065011/
https://www.ncbi.nlm.nih.gov/pubmed/24949995
http://dx.doi.org/10.1371/journal.pone.0099991

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