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A Highly Functional Synthetic Phage Display Library Containing over 40 Billion Human Antibody Clones

Several synthetic antibody phage display libraries have been created and used for the isolation of human monoclonal antibodies. The performance of antibody libraries, which is usually measured in terms of their ability to yield high-affinity binding specificities against target proteins of interest,...

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Detalles Bibliográficos
Autores principales: Weber, Marcel, Bujak, Emil, Putelli, Alessia, Villa, Alessandra, Matasci, Mattia, Gualandi, Laura, Hemmerle, Teresa, Wulhfard, Sarah, Neri, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065035/
https://www.ncbi.nlm.nih.gov/pubmed/24950200
http://dx.doi.org/10.1371/journal.pone.0100000