High-Resolution Quantification of Hepatitis C Virus Genome-Wide Mutation Load and Its Correlation with the Outcome of Peginterferon-Alpha2a and Ribavirin Combination Therapy

Hepatitis C virus (HCV) is a highly mutable RNA virus and circulates as a heterogeneous population in individual patients. The magnitude of such population heterogeneity has long been proposed to be linked with diverse clinical phenotypes, including antiviral therapy. Yet data accumulated thus far a...

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Detalles Bibliográficos
Autores principales: Wang, Weihua, Zhang, Xiaoan, Xu, Yanjuan, Weinstock, George M., Di Bisceglie, Adrian M., Fan, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065037/
https://www.ncbi.nlm.nih.gov/pubmed/24950220
http://dx.doi.org/10.1371/journal.pone.0100131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065037/
https://www.ncbi.nlm.nih.gov/pubmed/24950220
http://dx.doi.org/10.1371/journal.pone.0100131

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