Generation and Characterization of an Nse-CreER(T2) Transgenic Line Suitable for Inducible Gene Manipulation in Cerebellar Granule Cells

We created an Nse-CreER(T2) mouse line expressing the tamoxifen-inducible CreER(T2) recombinase under the control of the neuron-specific enolase (Nse) promoter. By using Cre reporter lines we could show that this Nse-CreER(T2) line has recombination activity in the granule cells of all cerebellar lo...

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Detalles Bibliográficos
Autores principales: Pohlkamp, Theresa, Steller, Laura, May, Petra, Günther, Thomas, Schüle, Roland, Frotscher, Michael, Herz, Joachim, Bock, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065071/
https://www.ncbi.nlm.nih.gov/pubmed/24950299
http://dx.doi.org/10.1371/journal.pone.0100384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065071/
https://www.ncbi.nlm.nih.gov/pubmed/24950299
http://dx.doi.org/10.1371/journal.pone.0100384

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