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Proteomics Analysis of the Non-Muscle Myosin Heavy Chain IIa-Enriched Actin-Myosin Complex Reveals Multiple Functions within the Podocyte

MYH9 encodes non-muscle myosin heavy chain IIA (NMMHCIIA), the predominant force-generating ATPase in non-muscle cells. Several lines of evidence implicate a role for MYH9 in podocytopathies. However, NMMHCIIA‘s function in podocytes remains unknown. To better understand this function, we performed...

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Detalles Bibliográficos
Autores principales: Hays, Thomas, Ma’ayan, Avi, Clark, Neil R., Tan, Christopher M., Teixeira, Avelino, Teixeira, Angela, Choi, Jae W., Burdis, Nora, Jung, Sung Yun, Bajaj, Amol O., O’Malley, Bert W., He, John C., Hyink, Deborah P., Klotman, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065073/
https://www.ncbi.nlm.nih.gov/pubmed/24949636
http://dx.doi.org/10.1371/journal.pone.0100660