Degradation Study on Sulfasalazine and a Validated HPLC-UV Method for its Stability Testing

Sulfasalazine (SSZ) was subjected to degradation under the conditions of hydrolysis (acid, alkali, and water), oxidation (30% H(2)O(2)), dry heat, and photolysis (UV-VIS light) in accordance with the ICH guidelines. An RP-HPLC method was developed to study the degradation behavior. No degradation wa...

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Detalles Bibliográficos
Autores principales: Saini, Balraj, Bansal, Gulshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065124/
https://www.ncbi.nlm.nih.gov/pubmed/24959403
http://dx.doi.org/10.3797/scipharm.1311-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065124/
https://www.ncbi.nlm.nih.gov/pubmed/24959403
http://dx.doi.org/10.3797/scipharm.1311-15

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