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Dopamine Signaling in C. elegans Is Mediated in Part by HLH-17-Dependent Regulation of Extracellular Dopamine Levels

In Caenorhabditis elegans, the dopamine transporter DAT-1 regulates synaptic dopamine (DA) signaling by controlling extracellular DA levels. In dat-1(ok157) animals, DA is not taken back up presynaptically but instead reaches extrasynpatic sites, where it activates the dopamine receptor DOP-3 on cho...

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Detalles Bibliográficos
Autores principales: Felton, Chaquettea M., Johnson, Casonya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065251/
https://www.ncbi.nlm.nih.gov/pubmed/24709946
http://dx.doi.org/10.1534/g3.114.010819