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The contribution of dormant origins to genome stability: From cell biology to human genetics
The ability of a eukaryotic cell to precisely and accurately replicate its DNA is crucial to maintain genome stability. Here we describe our current understanding of the process by which origins are licensed for DNA replication and review recent work suggesting that fork stalling has exerted a stron...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065331/ https://www.ncbi.nlm.nih.gov/pubmed/24767947 http://dx.doi.org/10.1016/j.dnarep.2014.03.012 |