Cargando…
Dual regulation of β(2)-adrenoceptor messenger RNA expression in human lung fibroblasts by β(2)–cAMP signaling; delayed upregulated inhibitors oppose a rapid in onset, direct stimulation of gene expression
Based on their bronchodilatory effect, β(2)-adrenoceptor agonists constitute essential elements in the treatment of bronchial asthma and COPD. As treatment with β(2)-adrenoceptor agonists has been associated with worsening of airway hyper-reactivity, possibly because of loss of β-adrenoceptor functi...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065340/ https://www.ncbi.nlm.nih.gov/pubmed/24705868 http://dx.doi.org/10.1007/s00210-014-0971-7 |