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Association study of the ABCC8 gene variants with type 2 diabetes in south Indians

BACKGROUND: The ABCC8 gene which encodes the sulfonylurea receptor plays a major role in insulin secretion and is a potential candidate for type 2 diabetes. The -3c → t (rs1799854) and Thr759Thr (C → T, rs1801261) single nucleotide polymorphisms (SNPs) of the ABCC8 gene have been associated with typ...

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Detalles Bibliográficos
Autores principales: Venkatesan, Radha, Bodhini, Dhanasekaran, Narayani, Nagarajan, Mohan, Viswanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065476/
https://www.ncbi.nlm.nih.gov/pubmed/24959012
http://dx.doi.org/10.4103/0971-6866.132752