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microRNA-128a dysregulation in transgenic Huntington’s disease monkeys

BACKGROUND: Huntington’s Disease (HD) is a progressive neurodegenerative disorder with a single causal mutation in the Huntingtin (HTT) gene. MicroRNAs (miRNAs) have recently been implicated as epigenetic regulators of neurological disorders, however, their role in HD pathogenesis is not well define...

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Detalles Bibliográficos
Autores principales: Kocerha, Jannet, Xu, Yan, Prucha, Melinda S, Zhao, Dongming, Chan, Anthony WS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065582/
https://www.ncbi.nlm.nih.gov/pubmed/24929669
http://dx.doi.org/10.1186/1756-6606-7-46