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microRNA-128a dysregulation in transgenic Huntington’s disease monkeys
BACKGROUND: Huntington’s Disease (HD) is a progressive neurodegenerative disorder with a single causal mutation in the Huntingtin (HTT) gene. MicroRNAs (miRNAs) have recently been implicated as epigenetic regulators of neurological disorders, however, their role in HD pathogenesis is not well define...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065582/ https://www.ncbi.nlm.nih.gov/pubmed/24929669 http://dx.doi.org/10.1186/1756-6606-7-46 |