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Assessment and refinement of eukaryotic gene structure prediction with gene-structure-aware multiple protein sequence alignment
BACKGROUND: Accurate computational identification of eukaryotic gene organization is a long-standing problem. Despite the fundamental importance of precise annotation of genes encoded in newly sequenced genomes, the accuracy of predicted gene structures has not been critically evaluated, mostly due...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065584/ https://www.ncbi.nlm.nih.gov/pubmed/24927652 http://dx.doi.org/10.1186/1471-2105-15-189 |