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Identification of a gene signature of a pre-transformation process by senescence evasion in normal human epidermal keratinocytes

BACKGROUND: Epidemiological data show that the incidence of carcinomas in humans is highly dependent on age. However, the initial steps of the age-related molecular oncogenic processes by which the switch towards the neoplastic state occurs remain poorly understood, mostly due to the absence of powe...

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Detalles Bibliográficos
Autores principales: Martin, Nathalie, Salazar-Cardozo, Clara, Vercamer, Chantal, Ott, Louise, Marot, Guillemette, Slijepcevic, Predrag, Abbadie, Corinne, Pluquet, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065601/
https://www.ncbi.nlm.nih.gov/pubmed/24929818
http://dx.doi.org/10.1186/1476-4598-13-151