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Identification of a gene signature of a pre-transformation process by senescence evasion in normal human epidermal keratinocytes
BACKGROUND: Epidemiological data show that the incidence of carcinomas in humans is highly dependent on age. However, the initial steps of the age-related molecular oncogenic processes by which the switch towards the neoplastic state occurs remain poorly understood, mostly due to the absence of powe...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065601/ https://www.ncbi.nlm.nih.gov/pubmed/24929818 http://dx.doi.org/10.1186/1476-4598-13-151 |