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An affective disorder in zebrafish with mutation of the glucocorticoid receptor

Upon binding of cortisol, the glucocorticoid receptor (GR) regulates the transcription of specific target genes, including those that encode the stress hormones corticotropin-releasing hormone (CRH) and adrenocorticotropic hormone (ACTH). Dysregulation of the stress axis is a hallmark of major depre...

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Detalles Bibliográficos
Autores principales: Ziv, Limor, Muto, Akira, Schoonheim, Peter J., Meijsing, Sebastiaan H., Strasser, Daniel, Ingraham, Holly A., Schaaf, Marcel J.M., Yamamoto, Keith R., Baier, Herwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065652/
https://www.ncbi.nlm.nih.gov/pubmed/22641177
http://dx.doi.org/10.1038/mp.2012.64