An Overview of the Spindle Assembly Checkpoint Status in Oral Cancer

Abnormal chromosome number, or aneuploidy, is a common feature of human solid tumors, including oral cancer. Deregulated spindle assembly checkpoint (SAC) is thought as one of the mechanisms that drive aneuploidy. In normal cells, SAC prevents anaphase onset until all chromosomes are correctly align...

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Detalles Bibliográficos
Autores principales: Teixeira, José Henrique, Silva, Patrícia Manuela, Reis, Rita Margarida, Moura, Inês Moranguinho, Marques, Sandra, Fonseca, Joana, Monteiro, Luís Silva, Bousbaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065761/
https://www.ncbi.nlm.nih.gov/pubmed/24995269
http://dx.doi.org/10.1155/2014/145289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065761/
https://www.ncbi.nlm.nih.gov/pubmed/24995269
http://dx.doi.org/10.1155/2014/145289

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