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Elevated Circulation Levels of an Anti-angiogenic SERPIN in Patients with Diabetic Microvascular Complications Impairs Wound Healing through Suppression of Wnt Signaling

Wound healing, angiogenesis and hair follicle maintenance are often impaired in the skin of diabetic patients, but the pathogenesis has not been well understood. Here, we report that circulation levels of kallistatin, a member of the serine proteinase inhibitor (SERPIN) superfamily with anti-angioge...

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Detalles Bibliográficos
Autores principales: McBride, Jeffrey, Jenkins, Alicia, Liu, Xiaochen, Zhang, Bin, Lee, Kyungwon, Berry, William L., Janknecht, Ralf, Griffin, Courtney, Aston, Christopher E., Lyons, Timothy, Tomasek, James J., Ma, Jian-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065799/
https://www.ncbi.nlm.nih.gov/pubmed/24463424
http://dx.doi.org/10.1038/jid.2014.40