Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets

BACKGROUND: Circulating free fatty acids are often elevated in patients with type 2 diabetes (T2D) and obese individuals. Chronic exposure to high levels of saturated fatty acids has detrimental effects on islet function and insulin secretion. Altered gene expression and epigenetics may contribute t...

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Detalles Bibliográficos
Autores principales: Hall, Elin, Volkov, Petr, Dayeh, Tasnim, Bacos, Karl, Rönn, Tina, Nitert, Marloes Dekker, Ling, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065864/
https://www.ncbi.nlm.nih.gov/pubmed/24953961
http://dx.doi.org/10.1186/1741-7015-12-103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065864/
https://www.ncbi.nlm.nih.gov/pubmed/24953961
http://dx.doi.org/10.1186/1741-7015-12-103

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