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Ribosomal Oxygenases are Structurally Conserved from Prokaryotes to Humans

2-Oxoglutarate (2OG)-dependent oxygenases play important roles in the regulation of gene expression via demethylation of N-methylated chromatin components(1,2), hydroxylation of transcription factors(3), and of splicing factor proteins(4). Recently, 2OG-oxygenases that catalyze hydroxylation of tRNA...

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Detalles Bibliográficos
Autores principales: Chowdhury, Rasheduzzaman, Sekirnik, Rok, Brissett, Nigel C., Krojer, Tobias, Ho, Chia-hua, Ng, Stanley S., Clifton, Ian J., Ge, Wei, Kershaw, Nadia J., Fox, Gavin C., Muniz, Joao R. C., Vollmar, Melanie, Phillips, Claire, Pilka, Ewa S., Kavanagh, Kathryn L., von Delft, Frank, Oppermann, Udo, McDonough, Michael A., Doherty, Aiden J., Schofield, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066111/
https://www.ncbi.nlm.nih.gov/pubmed/24814345
http://dx.doi.org/10.1038/nature13263