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Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2

Ornithine decarboxylase (ODC) is the key enzyme in the polyamine biosynthetic pathway. ODC levels are controlled by polyamines through the induction of antizymes (AZs), small proteins that inhibit ODC and target it to proteasomal degradation without ubiquitination. Antizyme inhibitors (AZIN1 and AZI...

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Detalles Bibliográficos
Autores principales: Ramos-Molina, Bruno, Lambertos, Ana, Lopez-Contreras, Andrés J., Kasprzak, Joanna M., Czerwoniec, Anna, Bujnicki, Janusz M., Cremades, Asunción, Peñafiel, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066113/
https://www.ncbi.nlm.nih.gov/pubmed/24967154
http://dx.doi.org/10.1016/j.fob.2014.05.004