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Biased and G Protein-Independent Signaling of Chemokine Receptors

Biased signaling or functional selectivity occurs when a 7TM-receptor preferentially activates one of several available pathways. It can be divided into three distinct forms: ligand bias, receptor bias, and tissue or cell bias, where it is mediated by different ligands (on the same receptor), differ...

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Detalles Bibliográficos
Autores principales: Steen, Anne, Larsen, Olav, Thiele, Stefanie, Rosenkilde, Mette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066200/
https://www.ncbi.nlm.nih.gov/pubmed/25002861
http://dx.doi.org/10.3389/fimmu.2014.00277