Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique

Human induced pluripotent stem cells (iPSC) can be used to understand the pathological mechanisms of human disease. These cells are a promising source for cell-replacement therapy. However, such studies require genetically defined conditions. Such genetic manipulations can be performed using the nov...

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Detalles Bibliográficos
Autores principales: Chen, Wanjuan, Liu, Jingxin, Zhang, Longmei, Xu, Huijuan, Guo, Xiaogang, Deng, Sihao, Liu, Lipeng, Yu, Daiguan, Chen, Yonglong, Li, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066246/
https://www.ncbi.nlm.nih.gov/pubmed/24953032
http://dx.doi.org/10.1038/srep05404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066246/
https://www.ncbi.nlm.nih.gov/pubmed/24953032
http://dx.doi.org/10.1038/srep05404

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