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Three-dimensional super-resolution and localization of dense clusters of single molecules

When a single molecule is detected in a wide-field microscope, the image approximates the point spread function of the system. However, as the distribution of molecules becomes denser and their images begin to overlap, existing solutions to determine the number of molecules present and their precise...

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Detalles Bibliográficos
Autores principales: Barsic, Anthony, Grover, Ginni, Piestun, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066253/
https://www.ncbi.nlm.nih.gov/pubmed/24953078
http://dx.doi.org/10.1038/srep05388