GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses

Detailed understanding of the signaling intermediates that confer the sensing of intracellular viral nucleic acids for induction of type I interferons is critical for strategies to curtail viral mechanisms that impede innate immune defenses. Here we show that the activation of the microtubule-associ...

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Detalles Bibliográficos
Autores principales: Chiang, Hao-Sen, Zhao, Yun, Song, Joo-Hye, Liu, Song, Wang, Ninghai, Terhorst, Cox, Sharpe, Arlene H., Basavappa, Megha, Jeffrey, Kate L., Reinecker, Hans-Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066330/
https://www.ncbi.nlm.nih.gov/pubmed/24270516
http://dx.doi.org/10.1038/ni.2766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066330/
https://www.ncbi.nlm.nih.gov/pubmed/24270516
http://dx.doi.org/10.1038/ni.2766

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