Role of Transcription Factor Acetylation in Diabetic Kidney Disease

Nuclear factor (NF)-κB and signal transducer and activator of transcription 3 (STAT3) play a critical role in diabetic nephropathy (DN). Sirtuin-1 (SIRT1) regulates transcriptional activation of target genes through protein deacetylation. Here, we determined the roles of Sirt1 and the effect of NF-κ...

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Detalles Bibliográficos
Autores principales: Liu, Ruijie, Zhong, Yifei, Li, Xuezhu, Chen, Haibing, Jim, Belinda, Zhou, Ming-Ming, Chuang, Peter Y., He, John Cijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066331/
https://www.ncbi.nlm.nih.gov/pubmed/24608443
http://dx.doi.org/10.2337/db13-1810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066331/
https://www.ncbi.nlm.nih.gov/pubmed/24608443
http://dx.doi.org/10.2337/db13-1810

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