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Role of Transcription Factor Acetylation in Diabetic Kidney Disease

Nuclear factor (NF)-κB and signal transducer and activator of transcription 3 (STAT3) play a critical role in diabetic nephropathy (DN). Sirtuin-1 (SIRT1) regulates transcriptional activation of target genes through protein deacetylation. Here, we determined the roles of Sirt1 and the effect of NF-κ...

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Detalles Bibliográficos
Autores principales:	Liu, Ruijie, Zhong, Yifei, Li, Xuezhu, Chen, Haibing, Jim, Belinda, Zhou, Ming-Ming, Chuang, Peter Y., He, John Cijiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2014
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066331/ https://www.ncbi.nlm.nih.gov/pubmed/24608443 http://dx.doi.org/10.2337/db13-1810

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