Inhibition of SREBP Transcriptional Activity by a Boron-Containing Compound Improves Lipid Homeostasis in Diet-Induced Obesity

Dysregulation of lipid homeostasis is intimately associated with obesity, type 2 diabetes, and cardiovascular diseases. Sterol regulatory-element binding proteins (SREBPs) are the master regulators of lipid biosynthesis. Previous studies have shown that the conserved transcriptional cofactor Mediato...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Xiaoping, Xiaoli, Zong, Haihong, Abdulla, Arian, Yang, Ellen S.T., Wang, Qun, Ji, Jun-Yuan, Pessin, Jeffrey E., Das, Bhaskar C., Yang, Fajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066337/
https://www.ncbi.nlm.nih.gov/pubmed/24608444
http://dx.doi.org/10.2337/db13-0835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066337/
https://www.ncbi.nlm.nih.gov/pubmed/24608444
http://dx.doi.org/10.2337/db13-0835

Ejemplares similares