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Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans

Unacylated ghrelin (UAG) is the predominant ghrelin isoform in the circulation. Despite its inability to activate the classical ghrelin receptor, preclinical studies suggest that UAG may promote β-cell function. We hypothesized that UAG would oppose the effects of acylated ghrelin (AG) on insulin se...

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Detalles Bibliográficos
Autores principales: Tong, Jenny, Davis, Harold W., Summer, Suzanne, Benoit, Stephen C., Haque, Ahrar, Bidlingmaier, Martin, Tschöp, Matthias H., D’Alessio, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066344/
https://www.ncbi.nlm.nih.gov/pubmed/24550190
http://dx.doi.org/10.2337/db13-1598