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Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans
Unacylated ghrelin (UAG) is the predominant ghrelin isoform in the circulation. Despite its inability to activate the classical ghrelin receptor, preclinical studies suggest that UAG may promote β-cell function. We hypothesized that UAG would oppose the effects of acylated ghrelin (AG) on insulin se...
Autores principales: | Tong, Jenny, Davis, Harold W., Summer, Suzanne, Benoit, Stephen C., Haque, Ahrar, Bidlingmaier, Martin, Tschöp, Matthias H., D’Alessio, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066344/ https://www.ncbi.nlm.nih.gov/pubmed/24550190 http://dx.doi.org/10.2337/db13-1598 |
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